Registration Dossier
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EC number: 215-851-5 | CAS number: 1429-50-1
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- The study was conducted in accordance with OECD 105, but not in compliance with GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Key result
- Water solubility:
- 19.6 g/L
- Temp.:
- 20 °C
- pH:
- ca. 2.9 - ca. 3
- Remarks on result:
- other: The average water solubility was reached after 24 h and remains constant over the next 48 h.
- Conclusions:
- A water solubility of 19.6 g/l at 20°C was determined for the substance in accordance with OECD 105. The result is considered to be reliable.
Reference
Table 1: Result of preliminary study
ml of water for 0.1 g soluble |
0.1 |
0.5 |
1 |
2 |
10 |
100 |
>100 |
Approximate solubility in g/l |
>1000 |
1000 to 200 |
200 to 100 |
100 to 50 |
50 to 10 |
10 to 1 |
<1 |
Visual result |
Solids |
Solids |
Solids |
Solids |
Nearly clear |
Completely clear |
|
Table 2: Water solubility of EDTMP
|
Series 1 |
Series 2 |
||||
|
After 24 h |
After 48 h |
After 72 h |
After 24 h |
After 48 h |
After 72 h |
EDTMP [%] |
1.94 |
1.95 |
1.99 |
1.97 |
1.92 |
1.92 |
pH |
3.0 |
2.95 |
3.0 |
2.94 |
2.92 |
2.91 |
Density (g/cm3) |
- |
- |
1.008 |
- |
- |
1.008 |
EDTMP [g/l] |
19.5 |
19.6 |
20.0 |
19.8 |
19.4 |
19.4 |
Average |
19.7 |
19.5 |
||||
Standard deviation |
0.2645 |
0.2304 |
||||
Variation |
0.0466 |
0.0355 |
||||
Description of key information
Water solubility (EDTMP-H): 19.6 g/l at 20°C (OECD 105)
Key value for chemical safety assessment
- Water solubility:
- 19.6 g/L
- at the temperature of:
- 20 °C
Additional information
The substance EDTMP-H is known to be highly hydrophilic and extremely water-soluble. A measured water solubility of 19.6 g/L at 20°C was determined for the substance in accordance with OECD 105. The result is considered reliable and selected as key study.
Phosphonate salts are highly water soluble. In available secondary sources to which reliability could not be assigned, water solubility values of 21000 mg/L and 30 g/L at 25°C were reported for EDTMP-H.
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