Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
health surveillance data
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: No experimental data described. Published standard setting review by competent commission

Data source

Reference
Reference Type:
publication
Title:
Toluene diisocyanate
Author:
Greim H
Year:
2003
Bibliographic source:
In: Occupational Toxicants: Critical Data Evaluation for MAK Values and Classification of Carcinogens, Vol.20, 291-338, Wiley-VCH. (ISBN: 3-527-27797-8)

Materials and methods

Test material

Constituent 1
Reference substance name:
m-tolylidene diisocyanate
EC Number:
247-722-4
EC Name:
m-tolylidene diisocyanate
Cas Number:
26471-62-5
IUPAC Name:
2,4-diisocyanato-1-methylbenzene

Results and discussion

Applicant's summary and conclusion

Conclusions:
This standard setting by an expert group is used as the basis for DN(M)EL s used in section 7.