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Diss Factsheets
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EC number: 940-822-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The log Kow values of the majority of the constituents of the tested UVCB substance was determined to be above 6.2.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 6.2
- at the temperature of:
- 25 °C
Additional information
The log Kow of the UVCB substance was determined according to OECD and EU guidelines. The study was performed using a HPLC with a C18 column. Two reference substance mixes with six resp. seven reference substances with different retention times (including toluene resp. DDT as reference substance with the highest log Kow) and thiourea for the determination of the dead time were used to produce a calibration curve, since retention time on hydrophobic columns and Kow are correlated.
As the chromatogram of the test substance solution showed signals in the dead time of the method as well as at retention times below and higher than the retention time of DDT (log POW > 6.2), the determination was performed with three mobile phases:
- methanol/water 65/35 (%v/v) for the log Kow range of 0.3 to 2.7,
- methanol/water 75/25 (%v/v) for the log Kow range of 1.7 to 6.2, and
- 100 % methanol for constituents with a log Kow > 6.2.
The determinations with mobile phases methanol/water 65/35 (%v/v) and 75/25 (%v/v) showed signals below 5% of the total peak area only. The log Kow of the test substance is therefore stated as > 6.2.
It is to be noted that, due to extensive overlap of the signals in the chromatogram, it was not possible to determine log Kow values of individual constituents.
In order to further evaluate the outcome of the log Kow test on FAV-ES, the log kow value of each individual substance in the UVCB is estimated using EpiSuite.
The QSAR results show that the constituents of FAV-ES all have a log Kow value of 5.81 or higher. The estimated log Kow value is > 6.6 for all but one FAV-ES constituents. The constituent having an estimated log Kow of 5.81 only occurs in relevant concentrations in the crude grade composition.
The results of the QSAR assessment are in line with the findings of the log Kow test, i.e. the vast majority of the constituents of FAV-ES have a log Kow value > 6.2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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