Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 627-085-2 | CAS number: 1238449-42-7
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Enhanced readily biodegradable: > 70 % in 31 d (OECD 301B)
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable, fulfilling specific criteria
Additional information
Five studies investigation the ready biodegradability of Dipropylheptylcarbonate (CAS No. 1238449-42-7) are available.
The GLP key study was performed under aerobic conditions according to OECD guideline 301B using non-adapted domestic activated sludge as inoculum (Oggier, 2011). A test concentration of 10 mg/L was applied. CO2 evolution was quantified using TOC analysis. The test period was prolonged to 49 days. A biodegradation of 59.7 % was measured after a test period of 28 days. Thus, the test substance is not readily biodegradable according to OECD criteria. However, as a biodegradation of >60 % was reached after a test period of 31 days, the test substance can be judged enhanced readily biodegradable according to the "Guidance of information requirements and chemical safety assessment, R.7b" (ECHA, 2008). This result is confirmed by all additional studies.
Two supporting studies, which were performed under the same conditions as the key study reached biodegradation values of 28 % after a test period of 28 days (BASF, 2011; Ley, 2011). Both tests were prolonged in there test period and reached biodegradation values of ca. 80 % after 42 days (Ley, 2011) and 49 days (BASF, 2011), respectively.
Two further studies, which were conducted according to GLP and OECD guideline 310 (Fiebig, 2011) and 301B (Ley, 2010) without prolongation of the test period, support the assumption that the substance is not readily biodegradable. The studies resulted in biodegradation values of 22 % (Fiebig, 2011) and 54 – 55 % (Ley, 2010) after a test period of 28 days.
Based on all available data it can be concluded that bis(2-propylheptyl) carbonate requires a long lag phase of 15 -25 days befor the biodegradation reaction starts. However, once started the degradation is fast and leads to a complete mineralization without the formation of metabolies.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
