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EC number: 931-285-8
CAS number: -
General summary of effects of gasoline vapors at low concentrations
(experiments 1 -4)
All of the experiments showed that in groups of subjects there would
always be a few who might have minor complaints when placed in
concentrations of gasoline vapor detectable by smell. The complaints
were slight; one or two individuals invariably noticed some
gastrointestinal disturbance and the eye irritation was prominent. On
further inquiry it was found that the substance causing eye irritation
was distilled from gasoline at extremely low temperatures and in very
General summary of high concentration experiments (exp 5 -9):
These studies have shown that gasoline vapor in 0.1 percent
(approximately 4320 mg/m3) causes definitely unpleasant symptoms in a
few subjects at the end of an hour. These symptoms are not those of
exhilaration and drunkenness but are apt to be slight dizziness, nausea,
and headache. When the gasoline concentration reaches 0.26 percent
(approximately 12480 mg/m3), five subjects out of six remained under
exposure voluntarily for 1 h, and the five subjects were all drunk and
somewhat anesthetized. The sixth became nauseated at the end of 13
minutes and had to leave the room. When concentrations reach 1 percent
(approximately 51376 mg/m3), both whole gasoline and distillate cause
dizziness and drunkenness in about 5 minutes. The effect is abrupt and
unescapable. The heavy concentration experiments re-emphasize the fact
that the eye and throat irritating substance found in gasoline was lost
in our light fraction.
In a series of experiments focused on the evaluation of central nervous
system effects, human subjects were exposed to vapors of whole
commerical gasoline and gasoline distillate in increasing concentrations
(672 mg/m3 to 53725 mg/m3) and exposure periods (<10 min to 8 h). The
studies provide consistent results indicating that the degree of CNS
effects increased with both exposure level and duration. Exposure to
approximately 4320 mg/m3for an hour produced slight dizziness, nausea
and headache. Exposure for an hour at 12480 mg/m3 produced a condition
similar to drunkenness. At 53725 mg/m3, dizziness and drunkenness were
apparent within 5 minutes.
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