Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 404-290-3 | CAS number: 7216-95-7
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
When rainbow trouts (O. mykiss) were exposed to pentapotassium salt of DTPA, the 96-hour LC50 was >1000 mg/L.
Key value for chemical safety assessment
Additional information
Two acute freshwater fish studies were assessed for this endpoint. One study was conducted with rainbow trout (Oncorhynchus mykiss) exposed to the pentapotassium salt of DTPA, while the other study was conducted with bluegill sunfish (Lepomis machrochirus) exposed to the pentasodium salt of DTPA. Upon contact with water, these DTPA salts are expected to dissociate, thus, these test chemicals are considered essentially equivalent in aquatic environments. Both studies were found to be of good quality and were comparable to or equivalent to guideline studies. The acute test with the rainbow trout was a limit test that concluded that the 96 hour LC50 for pentapotassium DTPA was >1000 mg/L. The acute test with the bluegill sunfish concluded that the 96 -hour LC50 for pentasodium DTPA was 1115 mg/L, which is equivalent to 1292 mg/L pentapotassium DTPA following stoichiometric conversion. Since these toxicity results were conducted with two different fish species, the lower of the two values (>1000 mg/L) was selected as the key parameter for this endpoint.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
