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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Regarding results obtained for the mixed TDA and 2,4-TDA. It is necessary to make distinction between these two susbtances to evaluate the acute toxicity effects.

Key value for chemical safety assessment

Additional information

For 2,4 -TDA only one study, validity 2 and considered as key study, was available for skin irritation on Rabbit. No erythema and oedema were observed and substance was considered as no irritant for the skin.

Human data on local irritation/corrosion due to 2,4-TDA are not available. In Draize tests

with rabbits, the substance did not cause skin irritation and demonstrated only slight

conjunctival redness after instillation to the eye. Thus, labelling of the pure 2,4-TDA with R

36 (irritating to eye) according to current EU regulations is not appropriate.(European Union Risk Assessment Report, 28.05.2008)

Justification for classification or non-classification

Classification according to Annex I of the directive 67/548/EEC - R 36 Irritating to eyes

By CLP Cat 2A. Warning. Causes serious eye irritation.