Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Additional information:
Migrated from Short description of key information:
Based on a sensitisation rate of up to 100% in a M&K test toluene diamine is labelled R43 (may cause sensitisation by skin contact). In addition in
humans cross sensitivity to p-phenylene diamine has to be considered. Animal or human data on respiratory sensitisation is not available.
(Source: EU Risk Assessment, of 24.03.2006)

Justification for classification or non-classification

Classification according to Annex I of the directive 67/548/EEC

R 43 May cause sensitization by skin contact


Skin Sens Cat 1. Warning. May cause an allergic skin reaction.