Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 221-975-0 | CAS number: 3302-10-1
Endpoint summary
Administrative data
Description of key information
Additional information
3,5,5 -trimethylhexanoic acid is not acutely toxic to fish (LC50 > 100 mg/L), but acutely harmful to aquatic invertebrates and algae.
Fish:
Regarding fish acute toxicity, a 96-h LC50 of 122 mg/L was reported in the key study with the cold water fish rainbow trout (Oncorhynchus mykiss; Davi, 1996), confirmed in a second test using the same species with a 96 -h LC50 of 160 mg/L (Hoechst AG, 1979). For warm water fish the reported 96 -h LC50 was 190 mg/L (Lepomis gibbosus; Hoechst AG, 1979).
Aquatic invertebrates:
The following effect concentrations were determined in a GLP guideline study according to OECD 202. The test item concentrations were analytically verified.
Daphnia magna: 48 -h EC50: 68 mg/L
Algae:
The following effect concentrations were determined in a GLP guideline study according to OECD 201. The test item concentrations were analytically verified.
Pseudokirchneriella subcapitata: 72 -h ErC50: 81 mg/L; 72 -h NOEC: 10 mg/L
Microorganisms:
The key study on the effect of 3,5,5,-trimethylhexanoic acid was tested on activated sludge microoorganisms. The 3 -h EC50 of 470 mg/L indicates that disturbances in sewage treatment plants are not to be expected when 3,5,5,-trimethylhexanoic acid are introduced in appropriately low concentrations (Hoechst AG, 1989).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
