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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

Acutely harmful to aquatic algae and cyanobacteria.

Key value for chemical safety assessment

EC50 for freshwater algae:
32.7 mg/L
EC50 for marine water algae:
39 mg/L
EC10 or NOEC for freshwater algae:
15.1 mg/L

Additional information

The acute toxicity of MIPA (CAS 78-96-6) to aquatic algae and cyanobacteria was investigated in a test conducted according to DIN 38412, part 9, using Desmodesmus subspicatus as test organism (BASF AG, 1989). Based on growth rate, the 72h ErC50 was determined to be 32.3 mg/L (72h ErC10 = 14.7 mg/L) indicating the test substance to be acutely harmful to algae. Data were recalculated using ToxRat v3.3.0 (BASF SE, 2021). The test substance solutions were not neutralized.


The study was conducted without analytical monitoring. However, it is assumed that the test concentrations remained stable over the exposure period based on a high water solubility (miscible at any ratio; see IUCLID ch. 4.8), a low vapour pressure (0.63 hPa at 25 °C, see IUCLID ch. 4.6) a low Henry's Law constant (4.95E-05 Pa m³/mol, HENRYWIN v3.20, BASF SE, 2017) and a low adsorption potential (log Kow = -0.93, BASF AG, 1987; log Koc = 1.53, according to Franco&Trapp, BASF SE, 2021). The stability over the exposure period was additionally confirmed by an available acute toxicity study on fish conducted with analytical monitoring and a recovery rate of 96% (Brooke, 1984).