Registration Dossier
Registration Dossier
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EC number: 204-558-8 | CAS number: 122-62-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects up to the limit of water solubility (< 1 mg/L in aqua dest) for Scenedesmus subspicatus (OECD 201)
Key value for chemical safety assessment
Additional information
One study investigating the toxicity of Bis(2-ethylhexyl) sebacate (CAS 122-62-3) to freshwater algae is available. The study was conducted under static conditions according to OECD guideline 201 using Scenedesmus subspicatus as test organism (Mead & Sewell, 1994). The aqueous phase of a 1000 mg/L loading rate solution was removed for testing after stirring for 24 h. The test concentration was measured using TOC analysis; however, the analysis showed that the test substance is only poorly soluble in water. Thus, the measured concentration was not used as basis for the determination of an effect concentration. The EC50 value for growth rate is only given for a period of 24 h; however, the EC50 for biomass is given for a test period of 72 h. As the biomass related effect value is generally considered to be lower than the growth rate related effect value the study is judged to be appropriate to assess the toxicity of the substance to freshwater algae.
No significant growth rate inhibition (3%) was observed during the test period of 24 hours. No significant biomass inhibition (1%) was observed after 72 hours exposure time. Hence, the 72 h-EbC50 is determined to be >1000 mg/L loading rate based on the nominal test concentration.
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