Registration Dossier
Registration Dossier
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EC number: 403-730-1 | CAS number: 2687-96-9
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.002 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.009 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 2.22 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.241 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.024 mg/kg sediment dw
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.047 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
The experimental values for aquatic organisms exposed to N-(n-dodecyl) pyrrolidinone (LP-300) are consistently lower than the QSAR estimated values (see the table below). The table below shows the ecotoxicity test results obtained with Surfadone LP300 alongside QSAR generated results based on the neutral organic SAR and Amides from ECOSAR v1.11 and on the individual phys-chem data. The experimental value of long-term exposure of fish of 0.018 mg/L is almost equal to the predicted value of 0.015 mg/L. Further, fish appears to be the most sensitive of the three trophic levels. Hence this value of 0.018 mg/L is used to calculate the respective PNECs.
| LP-300 | acute E(L)C50 | ||
| Species | Experimental | ECOSAR Version 1.10 Results | |
| Neutral Organic SAR | Amides | ||
Fish |
0.59 | 3.13 | 2.68 |
| Daphnia | 0.139 | 2.14 | 1.160 |
| Algae | 0.053 | 3.46 | 0.13 |
| Chronic Value | |||
| Experimental | Neutral Organic SAR | Amides | |
| Fish | 0.018 | 0.381 | 0.015 |
| Daphnia | 0.046* | 0.352 | 0.248 |
| Algae | 0.046 | 1.38 | 0.288 |
* Based on acute data.
Conclusion on classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
