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EC number: 231-146-5 | CAS number: 7440-36-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Additional information
During the slow transformation of Sb2O3 in soil into soluble Sb, the bioavailable Sb concentration (i.e. Sb in soil solution) will gradually increase and there will, as a consequence, not be a constant “toxic pressure” during the exposure period. As long as full equilibrium is not reached, the total Sb toxicity will be underestimated. However, the use of soluble Sb salts for toxicity testing introduces other changes in soil chemistry, besides increasing the concentration of Sb, such as increased concentrations of counter ions (e. g. chloride, sulphate) and protons. These changes in soil chemistry also have the potential to affect the observed toxic response.
At TC NES I ´07 it was concluded that the preferred exposure regime for terrestrial toxicity studies is sufficiently aged soil spiked with Sb2O3. This would ensure i) a constant Sb pore water concentration (i.e. constant toxic pressure) during the entire test period and ii) avoids toxic effects due to increased concentrations of counter ions and/or protons.
TC NES I ´07 decided that both the critical NOECs on plants (Oorts et al., 2005; 5.8 mg Sb/kg dw) and invertebrates (Kuperman et al.,2002; Phillips et al., 2002; both 58 mg Sb/kg dw) would be overruled by the results of new plant and invertebrate tests, if the latter were considered valid. Two new toxicity studies, which are both considered valid and were performed in the same Sb2O3-spiked and sufficiently aged soil, generated the toxicity data for invertebrates, plants and microrganisms that are used to derive the PNECsoil (and thereby overrule the results by Oorts et al. (2005), Kuperman et al. (2002), and Phillips et al. (2002)).
The first of these two studies was performed by Smolders et al. (2007) and reported on the endpoints of lettuce emergence and growth (ISO 11269-2), barley root elongation (ISO 11269-1), and nitrification rate (ISO 14238). The second study was performed by Moser (2007) and reported on the endpoints of mortality and reproduction of Folsomia candida (ISO 11267).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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