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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

long-term toxicity to fish, other
EPA 821-R-02-012
Type of information:
experimental study
Adequacy of study:
key study
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
equivalent or similar to guideline
other: Modified U.S. Environmental Protection Agency. 2002. Methods for measuring the acute toxicity of effluents and receiving waters to freshwater and marine organisms, 5th ed. EPA-821-R-02-012. Office of Water, Washington, DC
GLP compliance:
not specified
Test organisms (species):
Pimephales promelas
Test type:
Water media type:
Total exposure duration:
10 d
10 d
Dose descriptor:
Effect conc.:
2.2 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
Remarks on result:
other: 95% CL

LC50 (10 d): > 9.17 — < 10.22 µmol/L test mat. (meas. (geom. mean)) based on: mortality (95% CL)

Description of key information

Median lethal concentration of 9.68 µmol/L (2.20 mg/L; 95% CL, 9.17 -10.22 µmol/L) was calculated in 10 -d experiments.

LC50: 2.20 mg/L

Key value for chemical safety assessment

Additional information