Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 205-476-5 | CAS number: 141-27-5
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 974
Materials and methods
- Study type:
- study with volunteers
- Principles of method if other than guideline:
- A maximization test was carried out on 25 healthy male and female volunteers. The test material was applied under occlusion to the same site on the forearms of all subjects for five alternate-day 48-hour periods. The patch sites were pretreated for 24 hours with 5% aqueous sodium lauryl sulfate under occlusion. Challenge sites were read at patch removal and 24 hours after patch removal.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Geranial
- IUPAC Name:
- Geranial
Constituent 1
Method
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- Vehicle was petrolatum
5 % sensitization effects
20/25 positive.
Applicant's summary and conclusion
- Conclusions:
- 5 % sensitization effects
20/25 positive.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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