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Diss Factsheets
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EC number: 943-325-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24 November 2016 to 24 April 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 3,3'-[ethylenebis[(3-sulpho-p-phenylene)azo]]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:6)
- Cas Number:
- 75701-36-9
- IUPAC Name:
- 3,3'-[ethylenebis[(3-sulpho-p-phenylene)azo]]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:6)
- Test material form:
- solid: granular
Constituent 1
- Radiolabelling:
- no
Study design
- Analytical monitoring:
- yes
- Details on sampling:
- - Sampling time for parent: at 0, 24 and 120 hours in duplicate
- Sample storage conditions before analysis: no data
Duplicate aliquots (A and B) of each sample solution were diluted by a factor of 10 using acetonitrile: relevant buffer (1:9 v/v). - Buffers:
- -pH 4
Citric acid 0.006 mol/dm3
Sodium chloride 0.004 mol/dm3
Sodium hydroxide 0.007 mol/dm3
pH 7
Disodium hydrogen orthophosphate (anhydrous) 0.003 mol/dm3
Potassium dihydrogen orthophosphate 0.002 mol/dm3
Sodium chloride 0.002 mol/dm3
pH 9
Disodium tetraborate 0.001 mol/dm3
Sodium chloride 0.002 mol/dm3 - Details on test conditions:
- Pre-test
- Measures taken to avoid photolytic effects: shielded from light
- Measures to exclude oxygen: ultrasonication and degassing with nitrogen
- Nominal cocnentration: 4.0 g/L
- Temperature: 50.0 ± 0.5 °C
Duration of testopen allclose all
- Duration:
- 120 h
- pH:
- 4
- Temp.:
- 50 °C
- Initial conc. measured:
- >= 3.42 - <= 3.51 g/L
- Duration:
- 120 h
- pH:
- 7
- Temp.:
- 50 °C
- Initial conc. measured:
- >= 4.02 - <= 4.03 g/L
- Duration:
- 120 h
- pH:
- 9
- Temp.:
- 50 °C
- Initial conc. measured:
- 3.98 g/L
- Number of replicates:
- 2/pH
- Positive controls:
- no
- Negative controls:
- no
- Statistical methods:
- NA
Results and discussion
- Preliminary study:
- only a pre-liminary study was performed
- Test performance:
- The substance is stable at pH 4 (recovery after 5 days at 50°C: 102-106%), pH 7 (recovery after 5 days at 50°C: 111%) and pH 9 (recovery after 5 days at 50°C: 111%)
- Transformation products:
- not measured
- Remarks:
- the substance is hydrolytically stable
Dissipation DT50 of parent compound
- Remarks on result:
- hydrolytically stable based on preliminary test
Any other information on results incl. tables
pH 4
Time (Hours)
|
Concentration (g/L)
|
% of mean initial concentration |
||
|
A |
B |
A |
B |
0 |
3.42 |
3.51 |
- |
- |
24 |
3.62 |
3.76 |
104 |
109 |
120 |
3.54 |
3.68 |
102 |
106 |
pH 7
Time (Hours)
|
Concentration (g/L)
|
% of mean initial concentration |
||
|
A |
B |
A |
B |
0 |
4.02 |
4.03 |
- |
- |
24 |
4.01 |
4.02 |
99.6 |
99.9 |
120 |
4.45 |
4.47 |
111 |
111 |
pH 9
Time (Hours)
|
Concentration (g/L)
|
% of mean initial concentration |
||
|
A |
B |
A |
B |
0 |
3.98 |
3.98 |
- |
- |
24 |
4.05 |
4.06 |
102 |
102 |
120 |
4.43 |
4.43 |
111 |
111 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The substance is stable for > 1 year at pH 4, 7 and 9 at 25 °C
- Executive summary:
In a preliminary hydrolysis study the substance was incubated at pH 4, 7 and 9 at 50 °C during 120 hours. The hydrolysis was less than 10% after 5 days at 50 °C, equivalent to a half-life greater
than 1 year at 25 °C
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