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Diss Factsheets
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EC number: 943-325-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 19 September 2005 to 18 October 2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: guideline study under GLP
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.9 (Biodegradation: Zahn-Wellens Test)
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: waste water treatment plant ARA Ergolz II, Fuellinsdorf, Switzerland
- Storage length: not indicated
- Sorage condition: aerated at room temperature
- Preparation of inoculum for exposure: washed twice with tap water, supernatant decanted, homogenized and dried
- Pretreatment: none
- Concentration of sludge: 4 g dry weight/L
- Water filtered: no
- Ratio inoculum/test substance (as DOC): 3:1 - Duration of test (contact time):
- 28 d
- Initial conc.:
- 280 mg/L
- Based on:
- test mat.
- Initial conc.:
- ca. 100 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST CONDITIONS
- Composition of medium: accoding to the guideline
- Test temperature: 21-25 °C
- pH: 6.5-7.6 (measured at start and before each sampling)
- pH adjusted: if necessary to pH 7.1 to 7.9 (both in test substance vessels and controls)
- Aeration of dilution water: yes
- Suspended solids concentration: not determined
- Continuous darkness: yes
TEST SYSTEM
- Culturing apparatus: 2000 mL Erlenmeyer with 1000 mL testsolution (water and evaporation losses were compensated if necessary)
- Number of culture flasks/concentration: 2 for test substance, 2 for inoculum controls, 2 for reference controls, 1 toxicity control, 1 sterility control
- Method used to create aerobic conditions: not fully closed vessels and continuously stirring with magnetic stirrer
- Oxygen concentration: 6.7-8.9 mg/L (measured at start and before each sampling)
- Measuring equipment: TOC-analyzer
SAMPLING
- Sampling frequency: after 3 hours and on day 3, 7, 10, 14, 21 and 28
- Sampling method: no details
- Sterility check if applicable: included
- Sample storage before analysis: analysed immediately
CONTROL AND BLANK SYSTEM
- Inoculum blank: 2
- Abiotic sterile control: 1
- Toxicity control: 1 - Reference substance:
- diethylene glycol
- Test performance:
- All values are corrected for the degradation measured in inoculum controls.
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 12
- Sampling time:
- 3 d
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- >= 50 - <= 53
- Sampling time:
- 7 d
- Remarks on result:
- other: from day 7 to 28
- Details on results:
- Toxicity controls 74% degradation within 14 days (based on DOC of 190.3 mg/L 49% test substance and 51% reference substance)
No degrdation in abiotic controls
No DOC removal during the first 3 hours of the test --> indicative for no adsorption - Results with reference substance:
- The degradation of the reference substance was 100% after 7 days.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- The substance is inherently biodegrdable
- Executive summary:
In a Zahn-Wellens/EMPA test a biodegradation of 53% was observed for the substance (initial concentration 280 mg/L).No toxicity was towards micto organism was found. As the degradation is > 35% the substance is considered inherently biodegradable.
Reference
Description of key information
In a Zahn-Wellens/EMPA test (RCC 2005) a biodegradation of 53% was observed for the substance (initial concentration 280 mg/L).No toxicity was towards micro-organisms was found. As the degradation is > 35% the substance is considered inherently biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable
Additional information
In addition in a limited reported Zahn-Wellens test (BASF 1988) the substance degraded up to 60%, which confirms the finding that the substance is inherently biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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