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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Justification for type of information:
Method considered suitable to determine rish of inhaltion
Substance is typically supplied wetted (in mixture) to avoid dust formation.
Qualifier:
equivalent or similar to guideline
Guideline:
ISO 21501-2 (Determination of particle size distribution - Single particle light interaction methods - Part 2: Light scattering liquid-borne particle counter)
Principles of method if other than guideline:
Was carried out using a Malvern Mastersizer version 5.22
GLP compliance:
not specified
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
mass based distribution
Mass median aerodynamic diameter:
> 10 µm
Percentile:
D50
Mean:
> 10 µm
Remarks on result:
other: Low inhalable fraction
No.:
#1
Size:
1 µm
Distribution:
1.52 %
No.:
#2
Size:
4 µm
Distribution:
12 %
No.:
#3
Size:
10 µm
Distribution:
29.18 %
No.:
#4
Size:
32 µm
Distribution:
65.36 %
No.:
#5
Size:
60 µm
Distribution:
86.45 %
No.:
#6
Size:
75 µm
Distribution:
91.8 %
No.:
#7
Size:
110 µm
Distribution:
96.83 %
No.:
#8
Size:
145 µm
Distribution:
97.97 %
No.:
#9
Size:
160 µm
Distribution:
98.01 %
Conclusions:
Although there is significant proportion of material < 10 um, only a small proportion was under 1 um

It is considered to be medium dustiness for the CSR purposes.

Description of key information

The particle size distribution at 1 µm was 1.52  %       

Although there is significant proportion of material < 10 um, only a small proportion was under 1 um

It is considered to be medium dustiness for the CSR purposes.

Additional information

No. Size Distribution Remarks
#1 1 µm 1.52 %
#2 4 µm 12 %
#3 10 µm 29.18 %
#4 32 µm 65.36 %
#5 60 µm 86.45 %
#6 75 µm 91.8 %
#7 110 µm 96.83 %
#8 145 µm 97.97 %
#9 160 µm 98.01 %