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EC number: 208-719-3 | CAS number: 539-48-0
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 2017-10-23 to 2017-11-06
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- Pow
- Partition coefficient:
- 0.56
- Temp.:
- 25 °C
- pH:
- 6.5
- Remarks on result:
- other: Calculated from the six results
- Details on results:
- The partition coefficient (n-octanol/water) Pow of test item at 25°C was 0.56, logPow was -0.25. The range of six results was 0.06 lg units.
- Conclusions:
- The partition coefficient (n-octanol/water) Pow of test item at 25°C was 0.56, logPow was -0.25.
- Executive summary:
The Partition Coefficient (n-octanol/water) of test item was determined compatible with the Principles of OECD Guidelines for Testing of Chemicals No. 107 'Partition Coefficient (n-octanol/water): Shake Flask Method'. Based on the test results, the Powof test item at 25 °C was 0.56, logPowwas -0.25.
Reference
The Partition Coefficient (n-octanol/water) Results of test item
Stage groups |
Replicates |
Concentration of test item in saturated n-octanol(mg/L) |
Concentration of test item in saturated water (mg/L) |
Partition coefficient (Pow) |
logPow |
Stage 1 (1:1) |
1 |
1149.4 |
1987.29 |
0.58 |
-0.24 |
2 |
1153.0 |
2013.07 |
0.57 |
-0.24 |
|
Stage 2 (2:1) |
1 |
879.8 |
1647.95 |
0.53 |
-0.28 |
2 |
872.7 |
1669.76 |
0.52 |
-0.28 |
|
Stage 3 (1:2) |
1 |
1262.4 |
2115.36 |
0.60 |
-0.22 |
2 |
1271.6 |
2201.44 |
0.58 |
-0.24 |
|
Average |
0.56 |
-0.25 |
|||
Range of logPowwas 0.06 lg unit (n=6). |
|||||
Description of key information
The partition coefficient (n-octanol/water) Pow of test item at 25°C was 0.56, logPow was -0.25.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -0.25
- at the temperature of:
- 25 °C
Additional information
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