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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2021-03-05 - 2021-03-18
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2021

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Qualifier:
according to guideline
Guideline:
other: USP <429>
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution

Test material

Constituent 1
Chemical structure
Reference substance name:
(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-aminium sulfate
EC Number:
917-270-9
Cas Number:
29790-50-9
Molecular formula:
C36H80N2O10S
IUPAC Name:
(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-aminium sulfate
Test material form:
solid

Results and discussion

Particle sizeopen allclose all
Percentile:
D10
Mean:
ca. 2 µm
Remarks on result:
other: D10 is the average of 3 measurements, no standard deviation for the average is written
Key result
Percentile:
D50
Mean:
ca. 15 µm
Remarks on result:
other: D50 is the average of 3 measurements, no standard deviation for the average is written
Percentile:
D90
Mean:
ca. 425 µm
Remarks on result:
other: D90 is the average of 3 measurements, no standard deviation for the average is written

Any other information on results incl. tables

 




































Volume Distribution Q3



d10
[µm]



d50
[µm]



d90
[µm]



 



1.909



13.03



408.6



 



2.326



16.60



426.6



 



2.316



15.33



438.9



Mean:



2.184



14.99



424.7



 


The average of three measurements is:                   


d10:                 2 µm


d50:               15 µm


d90:               425 µm

Applicant's summary and conclusion

Conclusions:
The average particle size (volume distribution) of the test item is d10: 2 µm, d50: 15 µm, d90: 425 µm
Executive summary:

The particle size distribution (volume distribution) of Phytosphingosine sulfate was measured by laser diffraction in air. The average of three measurements is: d10: 2 µm, d50: 15 µm, d90: 425 µm