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EC number: 235-384-0 | CAS number: 12207-63-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
One reliable long-term toxicity study (Klimisch 2) of vanadium substances to sediment organisms was identified: In a chronic sediment toxicity test acc. to US EPA test method 100.4, Hyalella azteca (7-14 d old) were exposed to vanadium in field-contaminated sediments or in spiked natural sediment collected from Lake Catherine (Arkansas, USA) for 28 days and effects on survival and growth were assessed (Bennett, 2016). In the spiked sediment toxicity test, 28-d LC10 and LC50 values of 417 and 742 mg V/kg sediment dw (measured) were determined, respectively. Effects on the relative growth rate of H. azteca were observed only at the measured concentration of 626 mg V/kg (LOEC) but not at 1269 mg V/kg. However, a 28-d NOEC of 498 mg V/kg sediment dw (measured) could be derived for growth rate.
Contrary to effects observed in spiked sediments, effects on mortality or growth of H. azteca could not be observed in the same study with field-contaminated sediments with substantially higher measured sediment V concentrations of up to 1826 mg V/kg. Field sediments were collected from 9 different sites at Lake Catherine (including control) in June and October 2015. Measured V concentrations of 12 out of 18 collected sediment samples were > 417 mg V/kg sediment d.w. (i.e. LC10 of H. azteca in laboratory spiked sediments). The absence of effects in field-contaminated sediments with substantially higher vanadium concentrations suggests that the bioavailability and toxicity of vanadium is much lower in field contaminated than in laboratory-spiked sediments (equilibrated for 14 days). The corresponding pore water analysis confirmed that measured V(V) concentrations of pore water of site sediments were < 1 µg/L for all sites, whereas pore water concentrations of spiked sediments were significantly higher (e.g. at the LC10: 371 µg V/L). Furthermore, significantly higher iron and organic carbon levels were determined in field sediments compared to spiked sediments, which also supports the assumption that vanadium was more bioavailable in laboratory-spiked sediments. Results from field-contaminated sites are thus considered more relevant for the hazard assessment of vanadium, since equilibrium was presumably not reached in laboratory-spiked sediments so that bioavailability and consequently toxicity were thus overestimated.
A reliable short term-toxicity test (Nedrich et al. 2018; Klimisch 2), in which 7-9 day old Hyalella azteca were exposed to vanadium in two field-collected sediments with respective background V concentrations of 807.45 and 1124.72 mg V/kg dry weight. Significant effects on survival and growth compared to a control sediment (31.24 mg V/kg) and a reference-site sediment (118.16 mg V/kg) were not observed in a sediment-filled microcosm after 7 days.
Additionally, significant toxic effects on growth and survival to Hyalella azteca were not observed in a 10-day test in field-contaminated sediments enriched with V up to 503 and 1590 mg V/kg dry weight and molybdenum by metallurgical activities (supporting study by Conestoga-Rovers & Associates, 2009; Klimisch 3).
All three studies on the toxicity of vanadium in field-contaminated sediments with high background V concentrations can be considered as supporting studies for the hazard assessment of vanadium since mixture toxicity of field-collected sediments cannot be excluded.
Key value for chemical safety assessment
Additional information
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