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EC number: 240-464-3 | CAS number: 16415-12-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Terrestrial toxicity studies with hexadecyl(trimethoxy)silane (CAS No. 16415-12-6) are available for soil macroorganisms (acute and chronic), terrestrial plants (chronic), and soil microorganisms (chronic).
The available acute toxicity study to earthworms (OECD 207) resulted in an LC50 (14 d) of > 1000 mg/kg soil dw whereas in the chronic toxicity study with earthworm (OECD 222) effects on biomass and reproduction were observed (NOEC = 500 mg/kg soil dw).
In the seedling emergence and seedling growth test, the toxicity to six terrestrial plant species was tested according to OECD 208 and no significant differences for shoot height, number of emerged seedlings and survival of plants were observed for all tested plant species. Oats and lettuce were the most sensitive plant species and showed a statistically reduced shoot fresh weight after 21 days. For these species the NOEC is 250 mg/kg dw.
One GLP study is available testing the effects of the test substance on nitrogen transformation in soil according to OECD 216. A significant inhibition of the microbial nitrate transformation was observed for test item concentrations ≥ 100 mg/kg soil dw. The corresponding no-observed effect concentration (NOEC) was 31.6 mg/kg soil dw which is the lowest effect value derived among terrestrial species.
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