Registration Dossier
Registration Dossier
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EC number: 200-657-5 | CAS number: 67-51-6
Endpoint summary
Administrative data
Description of key information
Additional information
Hydrolysis:
The half-life for hydrolysis was determined to be > 1 year at 25 ºC for 3,5-Dimethylpyrazole from pH 4 to 9. This was determined in a key study (Baltussen, 2012) which was performed in line with GLP and to the standardised guidelines OECD 111, EU method C.7 and EPA OPPTS 835.2120.
Biodegradation:
The biodegradability of 3,5-Dimethylpyrazole was determined in a key study (Kelly & Clayton, 2003) performed in line with GLP and to the standardised guidelines OECD 1301 A and EU method C.4 A. The test material was determined to be not readily biodegradable.
In accordance with Column 2 (specific rules for adaptation from Column 1) of Annex IX of Regulation (EC) No. 1907/2006, further degradation testing shall only be considered if the Chemical Safety Assessment indicates the need to investigate further the degradation of the substance.
The soil simulation testing (for substances with a high potential for adsorption to soil) test required under information point 9.2.1.3 does not need to be conducted since direct and indirect exposure of soil is unlikely. The identified uses of the substance are not likely to result in exposure to soil.
Bioaccumulation:
In accordance with Column 2 (specific rules for adaptation from Column 1) of Annex IX of Regulation (EC) No. 1907/2006, the bioaccumulation is aquatic species study, required under information point 9.3.2, can be omitted if direct and indirect exposure of the aquatic compartment is unlikely. No exposure to the aquatic environment is predicted, therefore testing is not required.
Transport and distribution:
The adsoption coefficient (Koc) for the substance was determined to be 1.2 x 105, giving a log Koc of 5.1. This large adsorption coefficient value demonstrates very little to no mobility through the soil of the chemical.
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