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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

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Description of key information

BCF of (2-Ethoxy-1-methyl-2-oxoethyl)-5-[2-chloro-4-(trifluoromethyl) phenoxy]-2-nitrobenzoate is 220-380 in whole fish. The substance is eliminated from the fish with an initial half-live of less than 1 d in fish when environmental supply is terminated

Key value for chemical safety assessment

BCF (aquatic species):
380 L/kg ww

Additional information

The bioconcentration potential of (2-Ethoxy-1-methyl-2-oxoethyl)-5-[2-chloro-4-(trifluoromethyl) phenoxy]-2-nitrobenzoate was determined in bluegill sunfish (Lepomis macrochirus) in a 44 d flow-through study with a constant concentration of 0.0087 mg/L 14C-labelled test item for a 30 d exposure period. Radioanalysis of whole fish, fillet and visceral portions throughout the exposure period indicated a rapid uptake

of 14C-(2-Ethoxy-1-methyl-2-oxoethyl)-5-[2-chloro-4-(trifluoromethyl) phenoxy]-2-nitrobenzoate. Bioaccumulation reached steady state after 3 d. At d 30 concentrations of 14C-(2-Ethoxy-1-methyl-2-oxoethyl)-5-[2-chloro-4-(trifluoromethyl) phenoxy]-2-nitrobenzoate were 2.2-3.7 ppm for whole fish, 0.24-0.91 ppm for fillet and 3.7-7.3 ppm for viscera. Elimination of 14C-(2-Ethoxy-1-methyl-2-oxoethyl)-5-[2-chloro-4-(trifluoromethyl) phenoxy]-2-nitrobenzoate was measured for 14 d by placing the fish into clean water. Clearance was 99, 94 and 99 % w/w for whole

fish, fillet and viscera, respectively .

Uptake-depuration was modeled for whole fish using a two-compartment kinetic model yielding a bioconcentration factor (BCF) of 220. With measured values of the 30th d, the BCF was 380 (whole body w.w.)