Registration Dossier
Registration Dossier
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EC number: 800-182-9 | CAS number: 1426148-68-6
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Three acute aquatic ecotoxicity values for all three trophic levels are available. Fish is the least sensitive species (LC0 (96h) 100 mg/L, LC50 (96h) > 100 mg/L) when compared to daphnia (EC50 (48h) 59 mg/L) and Algae (ErC50 (72h) 45 mg/L). So it can be expected that fish is also under chronic conditions is the least sensitive species. Based on this fact and for animal welfare reasons it is not justified and not warranted to carry out a chronic fish test.The assumption that fish is not the most sensitive species for alcohol ethoxylates is supported by the data available for other alcohol ethoxylates described in the HERA Risk Assessment (HERA Report Alcohol ethoxylaes from 2009,http://www.heraproject.com/files/34-F-09%20HERA%20AE%20Report%20Version%202%20-%203%20Sept%2009.pdf). In the HERA report the PNEC freshwater is also derived from the chronic Daphnia NOEC.
Calculation with ECOSAR v1.11 as part of EPISuite v4.11 by using the neutral organic class and the special class for surfactants-nonionic has been performed.
For the special class of nonionic surfactants only short-term acute values can be calculated which do not fit to the measured values. Therefore a calculation of chronic values is not possible.
The calculated ChV for fish in the neutral organic class is 39.14 mg/L.
As the calculated values for algae and daphnia fits well to the available chronic experimental data the calculated value for fish can be used and no further testing is neccessary.
Key value for chemical safety assessment
Additional information
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