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Diss Factsheets
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EC number: 203-472-8 | CAS number: 107-20-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of chloroacetaldehyde to the bacterium Pseudomonas putida was determined in a growth inhibition test according to the method described in the German Standard DIN 38412 Teil 8 and the International Standard ISO 10712. The study was carried out in according with the OECD principles of Good Laboratory Practice.
The concentrations of chloroacetyldehyde tested were 0, 6.5, 11, 20, 36, 62 and 111 mg/L. The concentrations given are nominal concentrations of chloroacetaldehyde. The growth was determined after 15.5 hours incubation at 23 +/- 1 °C by measuring the increase in absorbancy of the culture at 605 nm.
The effect values and their 95% confidence interval were calculated by a parametric model.
The EC10 with respect to bacterial growth after 15.5 hours was found to be 36.9 mg/L with a 95% confidence interval of 34.6-39.4 mg/L. This corresponds to an EC10 value of 17.0 mg/L (16.2-18.4 mg/L) with respect to the active ingredient.
The EC50 with respect to bacterial growth was found to be 44.7 mg/L with a 95% confidence interval of 35.1-57.0 mg/L. This corresponds to an EC50 value of 20.9 mg/L (16.4-26.7 mg/L) with respect to the active ingredient.
The test was valid as the increase in the control growth was sufficient and the EC50 of the reference substance 3,5-dichlorophenol had the expected value of 21.0 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 20.9 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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