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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2008-07-09 to 2008-08-13
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 170 Dry Sieve Analysis of Water Dispersible Granules
Version / remarks:
1994
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 169 Tap Density of Water Dispersible Granules
Version / remarks:
1994
Deviations:
no
Principles of method if other than guideline:
The sieve analysis consists of the quantitative separation of water dispersibel granules into fractions of different particle size ranges by use of machine sieving method.
GLP compliance:
yes (incl. QA statement)
Type of method:
sieving
Type of distribution:
other: mass distribution: machine sieving
Key result
Percentile:
D50
Mean:
>= 125 - <= 2 000 µm
Remarks on result:
other: no data about SD
No.:
#1
Size:
63 µm
Distribution:
0 %
No.:
#2
Size:
125 µm
Distribution:
0.2 %
No.:
#3
Size:
250 µm
Distribution:
0.6 %
No.:
#4
Size:
500 µm
Distribution:
4.3 %
No.:
#5
Size:
1 000 µm
Distribution:
24.2 %
No.:
#6
Size:
2 000 µm
Distribution:
70.6 %
No.:
#7
Size:
4 000 µm
Distribution:
0 %

The tap density (CIPAC MT 169) of TODI was found to be 0.75 g/mL.

The mass of the sample needed for the main test (m) was calculated to 105.5 g.

The particle size distribution of the test item was specified by the range [x1, x2] of two sieves where Rx1 >= 90% and Rx2 <= 10%.

Conclusions:
A range of 2000 to 1000 µm covers 90 % of the particle size distribution of TODI. No particles with a diameter below 63 µm were found.
Executive summary:

After determination of the tap density (0.75 g/mL), the particle size distribution of TODI was found to be [1000 µm; 2000 µm] applying machine sieving, specified by the range [x1, x2] of two sieves where Rx1 >= 90% and Rx2 <= 10%.

Seven sieves of sizes (µm) 63, 125, 250, 500, 1000, 2000 and 4000 were used.

Description of key information

A range of 2000 to 1000 µm covers 90 % of the particle size distribution of TODI. No particles with a diameter below 63 µm were found.

Additional information

After determination of the tap density (0.75 g/mL), the particle size distribution of TODI was found to be [1000 µm; 2000 µm] applying machine sieving, specified by the range [x1, x2] of two sieves where Rx1 >= 90% and Rx2 <= 10%.

Seven sieves of sizes (µm) 63, 125, 250, 500, 1000, 2000 and 4000 were used.