Registration Dossier
Registration Dossier
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EC number: 201-939-0 | CAS number: 89-78-1
Toxicity to birds
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to birds
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Description of key information
There are no data on avian toxicity available.
In accordance with section 1 of REACH Annex XI, the study does not need
to be conducted as avian toxicity data are used in the assessment of
secondary poisoning which is required for sub-stances indicating a
bioaccumulation potential. DL-Menthol has a low potential for
bioaccumulation (exp. BCF=<0.5 - 15), no adverse effects to birds due to
bioaccumulation in food chains would be expected.
Key value for chemical safety assessment
Additional information
No appropriate avian toxicology data are available for Menthol. Avian toxicity data are used in the assessment of secondary poisoning risks for the aquatic and terrestrial food chains. Secondary poisoning concerns the potential toxic impact of a substance on a predatory bird or mammal following ingestion of prey items (i.e. fish and earthworms) that contain the chemical. Accumulation of chemicals through the food chain may follow many different pathways along different trophic levels. As assessment is solely required for substances for which there is an indication for bioaccumulation potential (ECHA, R.7c, 2014). Bioconcentration factors (BCF) can be used for assessment. The experimental BCF value indicates no significant potential for bioaccumulation of Menthol in aquatic organisms. Furthermore, biodegradability of the substance strongly determines the ability of a substance to bioaccumulate in organisms. As Menthol is readily biodegradable no risk of bioaccumulation arises. Therefore, based on these properties no adverse effects to birds due to bioaccumulation in food chains would be expected and there is no need for testing.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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