Registration Dossier
Registration Dossier
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EC number: 201-280-9 | CAS number: 80-46-6
Endpoint summary
Administrative data
Description of key information
Additional information
Reliable measured biodegradation studies in water for p-tert-amylphenol and the analogue, p-tert-butylphenol are available and included in the dossier. Reliable biodegradation studies for sediment and soil are not available. Therefore, waivers are applied for these endpoints.
Reliable measured biodegradation studies for p-tert-amylphenol and the analogue, p-tert-butylphenol are available and included in the dossier. A reliable study by Haener (1999) showed that p-tert-amylphenol degraded 73% at the end of the 28 day test, although did not pass the 10-day window. A reliable study by Matthews and Schaefer (2013) showed that p-tert-butylphenol degraded 59% and 64%, in two different test concentrations, at 28 days, although did not pass the 10-day window.As per REACH Guidance Ch R.7.b, ready biodegradability tests can be used to prove inherent biodegradability when the pass level criterion is almost fulfilled (i.e., slightly below 60% degradation). Since degradation of 73% (Haener 1999) and 59% and 64% (Matthews and Schaefer 2013) occurred during the study, the test substance can be deemed inherently biodegradable. The key and supporting study results indicate that the test substance biodegrades rapidly once microbes have had a chance to acclimate. All effluents related to the use of p-tert-amylphenol will be through industrial WWTP as the substance is used as an intermediate. Any release to wastewater treatment plant or soil from residual p-tert-amylphenol in resin is negligible.
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