Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Hydrogen cyanide and soluble cyanide salts are not bioaccumulative in aquatic or terrestrial environments. The octanol-water partitioning coefficient (Kow) for hydrogen cyanide is not indicative of the potential for bioaccumulation, i.e., the log Kow of -0.25 for hydrogen cyanide is substantially less than the threshold log Kow of 3 or more that is indicative of the potential for bioaccumulation (ECHA, May 2008, Guidance on information requirements and chemical safety assessment, Chapter R.7, Endpoint-specific guidance, Section R.7.10.3.4). Callahan et al. (United States Environmental Protection Agency, 1979) state "there is little potential for bioaccumulation of hydrogen cyanides." A predicted BCF = 3.162 L/kg wet weight (log BCF = 0.500) was obtained from BCFBAF version 3.00, a QSAR model within U.S. EPA's EPISuite program; the BCF predictions of this model may be applied, for screening purposes, to organisms in aquatic and terrestrial environments. This predicted BCF is substantially below the threshold BCF values of >2000 L/kg and >5000 L/kg for classification as PBT and vPvB, respectively (ECHA, May 2008. Guidance on information requirements and chemical safety assessment, Chapter R.11, PBT Assessment, Table R.11 -1).