Registration Dossier
Registration Dossier
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EC number: 606-441-0 | CAS number: 201305-16-0
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
According to Regulation (EC) No. 1907/2006, Annex VIII, 9.1.3, short-term toxicity testing on fish does not need to be conducted if there are mitigating factors indicating that aquatic toxicity is unlikely to occur, for instance if the substance is highly insoluble in water. Benzoic acid, 4-hydroxy-, C18-22-alkyl esters (CAS No. 201305-16-0) is highly insoluble in water (water solubility < 0.05 mg/L) and exhibits a log Koc value of > 5. The Guidance on information requirements and chemical safety assessment, Chapter R7.b (ECHA, 2012) states that once insoluble chemicals enter a standard STP, they will be extensively removed in the primary settling tank and fat trap and thus, only limited amounts will get in contact with activated sludge organisms. Nevertheless, once this contact takes place, these substances are expected to be removed from the water column to a significant degree by adsorption to sewage sludge (Guidance on information requirements and chemical safety assessment, Chapter R.7a, (ECHA, 2012). Thus, discharged concentrations of this substance (if at all) into the aqueous compartment are likely to be low. Once present in the aquatic compartment, due to the low water solubility and high adsorption potential sediment is expected to be the main target for environmental distribution, and therefore the fraction available to fish via the water column is likely to be low.
Since it is expected that the concentration of Benzoic acid, 4-hydroxy-, C18-22-alkyl esters in water/sediment is low, the main environmental target compartment is soil. Considering this and animal welfare, a long-term earthworm test was conducted instead of a short-term fish test.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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