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Diss Factsheets

Physical & Chemical properties

Surface tension

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Reference
Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Study period:
08 Apr 2016
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
GLP guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.5 (Surface Tension)
Version / remarks:
adopted in 2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 115 (Surface Tension of Aqueous Solutions)
Version / remarks:
adopted in 1995
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
National Institute of Pharmacy and Nutrition, Budapest, Hungary
Type of method:
OECD harmonised ring method
Key result
Surface tension:
ca. 42.4 mN/m
Temp.:
20 °C
Remarks on result:
other: concentration was not accurately determined: 90% of the saturation solubility at 20 °C

Results

For the calculation of the surface tension of the test item, the mean of the measured surface tension values (see Table 1.) was corrected by the calibration factor and by the Harkins-Jordan correction (see Table 2.).

Table 1: Measured surface tension values and test conditions

 

Equilibrium time*

[sec]

Surface tension

[mN/m]

For the determination of equilibrium time

Do not consider for the calculation of the surface tension

300

42.4

320

42.9

340

43.9

360

44.2

420

44.1

480

44.1

 

420

44.1

 

420

44.1

 

420

44.0

 

420

44.0

 

420

44.0

Mean

 

44.0

 

* time after transferring the solution to the vessel until measuring the surface tension of the solution

 

Table 2: Calculation of the surface tension of LZ 53478


Calibration factor (φa)

1.0006

Surface tension values of LZ 53487 (σg)

44.0 mN/m

φa×σg

44.1 mN/m

Surface tension of aqueous solution of LZ 53478 after correction by Harkins-Jordan(interpolated value based on the guide REACH A.5)

42.4 mN/m

 

Conclusion

The surface tension of the aqueous solution of LZ 53478 is 42.4 mN/m.

As the surface tension value was below 60 mN/m, the test item is classified as surface active substance.

Description of key information

42.4 mN/m at 20.0 °C (OECD Guideline 115 (Surface Tension of Aqueous Solutions), EU Method A.5 (Surface Tension), OECD harmonised ring method)

As the surface tension value is below 60 mN/m, the test item is classified as surface active substance.

Key value for chemical safety assessment

Surface tension:
42.4

Additional information

Concentration was not accurately determined: 90% of the saturation solubility at 20 °C.