Registration Dossier
Registration Dossier
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EC number: 601-478-9 | CAS number: 117428-22-5
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.8 µg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.24 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.02 µg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 50 µg/kg sediment dw
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 1.86 µg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 14.8 µg/kg soil dw
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 6.67 mg/kg food
- Assessment factor:
- 30
Additional information
Conclusion on classification
The 96-hour LC50 for fish, the 48-hour EC50 for crustacea, and the 72-hour ErC50 for algae and other aquatic plants are <1 mg/L. The chronic NOECs for fish and crustacea are <0.1 mg/L. Additionally, the substance is considered not rapidly degradable and does not meet the criteria for a potential to bioaccumulate. Based on all the available data, the test substance is classified as Acute Cat 1 (H400: Very toxic to aquatic life) and Chronic Cat 1 (H410: Very toxic to aquatic life with long lasting effects) according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
In accordance with article 10 of the CLP Regulation (EC) No 1272/2008, if an M-factor is not yet given in Part 3 of Annex VI to the CLP Regulation, an M-factor should be determined and a scientific justification provided, when classifying substances for Acute Category 1 or Chronic Category 1. For this substance, adequate acute aquatic data are available in fish, aquatic invertebrates, and algae. An Acute M-Factor is based on the lowest reported effects in the most sensitive species, diatom. Therefore, the M factor is 100 based on the 96 h EC/LC50 of 0.0063 mg/L in diatoms.
In accordance with article 10 of the CLP Regulation (EC) No 1272/2008, if an M-factor is not yet given in Part 3 of Annex VI to the CLP Regulation, an M-factor should be determined and a scientific justification provided, when classifying substances for Acute Category 1 or Chronic Category 1. Chronic data were available in fish, invertebrates, and algae. The lowest reported effects in chronic data were the 21 d NOEC data of 0.008 mg/L in aquatic invertebrate. The test substance is Not biodegradable . Therefore, the M factor is 10.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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