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Diss Factsheets

Physical & Chemical properties

Flammability

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Administrative data

Endpoint:
flammable solids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
02 - 08 November 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
(2S,3S)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]bicyclo[2.2.2]octane-2-carboxylic acid
EC Number:
821-184-6
Cas Number:
1777721-60-4
Molecular formula:
C13H15ClFN3O2
IUPAC Name:
(2S,3S)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]bicyclo[2.2.2]octane-2-carboxylic acid
Test material form:
solid: particulate/powder
Details on test material:
- Name of test material (as cited in study reports): JNJ-63757096-AAA (T003689)
- Physical state: solid (powder)
- Appearance: white powder
Specific details on test material used for the study:
- Batch n°: I15BD0866
- Analytical purity: 99.0%
- Expiration date: 26 February 2017
- Storage condition: No specific handling conditions
required

Results and discussion

Flammable solids
Key result
Test procedure:
burning rate test: preliminary screening test
Remarks on result:
substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

Any other information on results incl. tables

In contact with the flame of the gas burner the test item did ignite. The test item melted, burned with a blue yellow flame and turned into black residue. White smoke was observed. After removal of the ignition source, the flame extinguished immediately and no propagation of combustion of the test item was observed.

According to the guidelines, performance of the burning rate test is not required. Based on the results obtained, the test item is considered ‘not readily combustible’ (i.e. ‘not flammable’).

Applicant's summary and conclusion

Interpretation of results:
not classified based on GHS criteria
Conclusions:
The preliminary screening test was performed for the determination of the flammability of JNJ-63757096-AAA (T003689) .

No propagation of combustion of the test item along 200 mm length of the pile within 2 minutes was observed. According to the guidelines, performance of the burning rate test is not required. Based on the results obtained, the test item is considered 'not readily combustible' (i.e. ‘not flammable’).