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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
density, other
Remarks:
density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
08 February 2018 - 29 March 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
pycnometer method

Test material

Constituent 1
Chemical structure
Reference substance name:
(2S,3S)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]bicyclo[2.2.2]octane-2-carboxylic acid
EC Number:
821-184-6
Cas Number:
1777721-60-4
Molecular formula:
C13H15ClFN3O2
IUPAC Name:
(2S,3S)-3-[(2-chloro-5-fluoropyrimidin-4-yl)amino]bicyclo[2.2.2]octane-2-carboxylic acid
Test material form:
solid: particulate/powder
Details on test material:
- Name of test material (as cited in study reports): JNJ-63757096-AAA (T003689)
- Physical state: solid (powder)
- Appearance: white powder
Specific details on test material used for the study:
- Batch n°: I16ED2695
- Analytical purity: 99.3%
- Expiration date: 28 May 2018
- Storage condition: At room temperature

Results and discussion

Density
Key result
Type:
density
Density:
1.46 g/cm³
Temp.:
20 °C
Remarks on result:
other: The difference between the results of the two measurements was < 0.02 g/cm³. According to the guideline, the density of the test item is therefore given as the mean value.

Any other information on results incl. tables

The density (ρ) of a substance is the quotient of its mass and its volume and is expressed in SI units of kg/m³.

The individual measurements were obtained with an accuracy of <0.02 g/cm³.

The individual density measurements were 1.457 g/cm³ (test 1) and 1.457 g/cm³ (test 2).

Applicant's summary and conclusion

Conclusions:
The density of the test item at 20ºC was 1.46 g/cm³ (1.46 x 10³ kg/m³).