Registration Dossier
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EC number: 700-672-1 | CAS number: 70226-26-5
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Reaction products of lauric acid and oxybis(propanediol) (List No. 700-627-1) can be considered as readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
There is no study available evaluating the biodegradability of the UVCB substance Reaction products of lauric acid and oxybis(propanediol) (List No. 700-627-1) in the environment. Therefore, the biodegradability of the test substance was assessed using read-across to the main components of the test substance, diglycerol mono- and dilaurate, and a structurally similar ester, which were linked in a weight of evidence approach. For the main components the biodegradability was assessed by QSAR calculations using BIOWIN v4.10. In addition one study report is available for the structurally similar UVCB substance Glycerides, C16-18, mono and di (CAS No. 67701-33-1). This read-across substance is comprised of monoesters and diesters of longer fatty alcohols compared to the ester in the test substance and thus can be considered as worst case scenario for the biodegradation of fatty acid ester components as occurring in the test substance.
The GLP study on the ready biodegradability of Glycerides, C16-18, mono- and diesters (CAS No. 67701-33-1) was conducted according to OECD 301D using predominantly domestic sewage and test substance concentrations of 2 and 5 mg/L. The substance reached 95% (2 mg/L) and 69% (5 mg/L) biodegradation after 28 days, fulfilling the 10-d window criterion. Therefore, Glycerides, C16-18, mono- and diesters can be considered as readily biodegradable.
QSAR calculations for the main components of the test substance using BIOWIN v4.10 resulted in a predicted ready biodegradability of both the monoester and the diester component of the test substance.
Given these results, Reaction products of lauric acid and oxybis(propanediol) (List No. 700-627-1) can be considered as readily biodegradable. This conclusion on ready biodegradability is in line with the recent assessment of substances as defined by the US-EPA HPV Aliphatic Diester Category (US-EPA, 2010).
US-EPA. 2010. Diesters Category of the Aliphatic Esters Chemicals (Test Plan and Robust Summaries for Substances in the HPV Test Plan). High Production Volume (HPV) Chemical Challenge Program (201-16837A and 201-16837B). accessed: http://www.epa.gov/hpv/pubs/summaries/alipestr/c13466tc.htm (04 Nov 2011)
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