Registration Dossier
Registration Dossier
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EC number: 240-759-7 | CAS number: 16712-64-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 96-hour LC50 of 3-HNA was above the highest test concentration of 82.2 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 82.2 mg/L
Additional information
Experimental data is available for a structural analogue of 6 -HNA, 3 -HNA. In a study with kilifish, the LC50 was above the highest test concentration of 82.2 mg/L. To verify whether 3 -HNA can be used as a surrogate for read-across purposes to 6 -HNA, two SAR estimations were conducted using Ecosar. The results clearly indicated a higher toxicity of 3 -HNA compared to 6 -HNA. Based on this, it is justified to use the toxicological data of 3 -HNA for read-across to 6 -HNA as they reflect a worst-case assumption.
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