Registration Dossier
Registration Dossier
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EC number: 240-759-7 | CAS number: 16712-64-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 63 mg/L
- EC10 or NOEC for freshwater algae:
- 7.21 mg/L
Additional information
Experimental data is available for a structural analogue of 6 -HNA, 3 -HNA. In a study with Pseudokirchneriella subcapitata, the EC50 for growth rate 63 mg/L. The NOEC for growth rate was 7.21 mg/L. To verify whether 3 -HNA can be used as a surrogate for read-across purposes to 6 -HNA, two SAR estimations were conducted using Ecosar. The results clearly indicated a higher toxicity of 3 -HNA compared to 6 -HNA. Based on this, it is justified to use the toxicological data of 3 -HNA for read-across to 6 -HNA as they reflect a worst-case assumption.
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