Registration Dossier
Registration Dossier
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EC number: 938-828-8 | CAS number: 1463474-95-4
Endpoint summary
Administrative data
Description of key information
Additional information
Based on the structure of HBED-Fe no hydrolysis is expected as no hydrolysable groups are present. The substance was therefore regarded as hydrolytically stable. This was confirmed by an actual study with HBED-Fe by Lange (2020). Identical results were observed for the structurally related EDDHMA-Fe and further supported by its application and use in aqueous solution and also by the read across substance EDDHA-FeNa which is also stable in water..
Abiotic degradation takes place predominately by photolysis as shown in studies with the structurally related EDDHMA-Fe. The half-life time for phototransformation of EDDHMA-FeNa at 25 +/- 3 degree C is determined to be 40.66 and 35.4 hours for the two major components of this UVCB substance, at a light intensity of 4.86E20 photons/second in the wavelength range of 290 - 500 nm.
Biodegradation of HBED-Fe or the structurally related EDDHMA-Fe and EDDHA-FeNa has not been shown in ready biodegradability tests.
A guideline study with HBED-Fe according to OECD guideline 301D showed less than 10% biodegradation of HBED-Fe after a prolonged incubation time of 60 days (van Ginkel, 2013). The lack of biodegradation does not mean that these substances are recalcitrant in nature because the stringency of the test procedures could account for the recalcitrance in these tests.
HBED-Fe is expected to have a low potential for bioaccumulation (HBED-Fe: logPow = -8.97).
Together with the high water solubility of HBED-Fe (> 10 g/L) the low observed sorption to soil (Landsberg, 2020) it is not expected to significantly adsorb to sediment and soil.
The latter is confirmed based on the according to OECD TG 106 measured Koc of 15.33 L/kg. These results were further confirmed by (non-guideline) experimental studies with structurally related EDDHMA and EDDHA.
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