Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 221-070-0 | CAS number: 2997-92-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Stability: thermal, sunlight, metals
Administrative data
- Endpoint:
- thermal stability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 07 December 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Determination of thermal stability by Differential Scanning Calorimetry (DSC).
- GLP compliance:
- no
Test material
- Reference substance name:
- 2,2'-azobis[2-methylpropionamidine] dihydrochloride
- EC Number:
- 221-070-0
- EC Name:
- 2,2'-azobis[2-methylpropionamidine] dihydrochloride
- Cas Number:
- 2997-92-4
- Molecular formula:
- C8H18N6.2ClH
- IUPAC Name:
- 2,2'-diazene-1,2-diylbis(2-methylpropanimidamide) dihydrochloride
- Test material form:
- solid
Constituent 1
Results and discussion
For thermal stability study
- Test substance thermally stable:
- no
Operating temperature
- Key result
- Operating temp.:
- 164.5 °C
- Remarks on result:
- other: exothermal event
Any other information on results incl. tables
RESULTS
- Safety pre-test 1: When heated on a magnesia groove over a Bunsen burner, the test substance fizzled with white smoke, melted to a yellow-brown liquid and burned with a yellow flame. When the test item was beaten with a hammer on the anvil, the test substance was compacted, no reaction was observed.
- Safety pre-test 2: The outside gold seal was grey-black discoloured and slightly bulged after reaching a temperature of 520 °C. After cooling, weight was recorded as 621.42 mg. When the crucible was opened, the test substance was charred, the gold seal was grey-black discoloured and
deformed.
- After calibration with indium and zinc the measurement of indium yielded the values shown in Figure 1 and Table 3.3-a (attached). The measurement of indium after calibration met the validity criteria.
- The DSC curve for the test item is shown in Figure 2 (attached).
- The DSC values for the test item are shown in Table 3.4-a (attached).
- Mass of the test item: 1.04 mg
- Mass of crucible before measurement: 616.86 mg,
- Mass of crucible after measurement: 616.13 mg.
- Observations: After the test the crucible was visually unchanged, the crucible was opened and the gold seal and the test item were discoloured black/grey.
Applicant's summary and conclusion
- Conclusions:
- During the DSC run an exothermal event caused by decomposition was observed at the temperature of 164.50 °C (onset) and this was integrated to derive the related energy (in J/g). The related energy of the observed exothermal event was 597.41 J/g.
- Executive summary:
Thermal stability of the test item was investigated by conducting a DSC (differential scanning calorimetry) screening test from 0 °C to 520 °C.
During the DSC run an exothermal event caused by decomposition was observed at the temperature of 164.50 °C (onset) and this was integrated to derive the related energy (in J/g). The related energy of the observed exothermal event was 597.41 J/g.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)