Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

In accordance with Regulation (EC) No 1907/2006 Annex VIII section 8.8.1, a toxicokinetics study is not required as assessment of the toxicokinetic behavior of the substance has been derived from the relevant available information.  This assessment is located within the endpoint summary for toxicokinetics, metabolism and distribution.

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential
Absorption rate - oral (%):
10
Absorption rate - dermal (%):
10
Absorption rate - inhalation (%):
10

Additional information

Considering the physico-chemical properties of N-(2-ethoxyphenyl)-N'-(2 -ethylphenyl)oxamide, it is expected to be absorbed via oral (assumed to be 10%),or dermal (assumed to be less than 10%) and inhalation (assumed to be 10%) exposure. Following absorption, the substance would be distributed most likely to the liver and kidney. The substance is expected to be subject to phase II metabolism to finally become excreted via bile and/or urine. Furthermore, it is believed that N-(2-ethoxyphenyl)-N'-(2-ethylphenyl)oxamide has low potential for accumulation in the body.

See attched report for details.