Registration Dossier
Registration Dossier
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EC number: 283-042-4 | CAS number: 84539-54-8
Endpoint summary
Administrative data
Description of key information
Additional information
General consideration
No experimental investigations of Fe(3Na)EDDHSA are available for relevant aquatic ecotoxicological endpoints. Read-across from the closely related substances Fe(3K)EDDHSA (EC 462-490-6), Fe(Na)EDDHA (CAS 84539-55-9) and Fe(Na)EDDHMA (CAS 84539-53-7) was performed instead. All substances show similar physico-chemical properties and are thus believed to behave very similar in aqueous solutions. For detailed information, please refer to the separate Read-across Statement.
Fish
The acute toxic effects of Fe(Na)EDDHA to zebrafish were investigated in a study according to the principles of OECD Guideline 203 and EU Method C.1. The LC50 for a 96 hour exposure was greater than 120 mg/L and the NOEC was greater than or equal to 120 mg/L for zebrafish.
Daphnia
The acute toxic effects of Fe(Na)EDDHA to Daphnia magna were investigated according to the principles of OECD-Guideline 202 and EU method C.2. The EC50 for a 48 hour exposure was greater than 120 mg/L based on the nominal concentration of the test substance and greater than 122 mg/L based on the mean measured concentrations.
In a long-term study, another structural analogue Fe(Na)EDDHMA had no effect on the survival of Daphnia magna at concentrations up to and including 1000 mg/L. Based on reproduction, a NOEC of 320 mg/L was derived. Based on parental mortality, the NOEC was found to be >= 1000 mg/L.
Algae
The 72 hour EC50 value for Fe(Na)EDDHA with the Desmodesmus subspicatus CHODAT (SAG 86.81) was greater than 294 mg/L and the NOEC was 8.2 mg/L based on mean measured concentrations and growth rate.
Aquatic plants
In a guideline study on the acute toxicity of Fe(Na)EDDHMA to Lemna minor the EC50-values for inhibition of log biomass growth (EbC50), specific growth rate (ErC50) and log biomass dry weight (EdwC50) were > 184.2 mg/L, the NOEC was 184.2 mg/L and the LOEC was > 184.2 mg/L.
Microorganisms
The 3 hours EC10 value for the test substance Fe(Na)EDDHA in the Activated Sludge Respiration Inhibition Test was 450 mg/L. The EC50 was greater than 1000 mg/L.
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