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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

According to a Mackay Level I model calculation, the main target compartment for isophorone diamine will be the hydrosphere (99.8 %), followed by sediment and soil (0.08 % each). The calculated Henry’s law constant of 0.000446 Pa m3/mol (HenryWin v3.10) indicates very low volatility of isophorone diamine from surface waters. With a calculated log Koc of 2.97 (pH 7), the sorption potential of isophorone diamine to soil or sediment organic matter is expected to be moderate (Blume scale).


 The QSAR calculated rate constant for the OH sensitized photodegradation of isophorone diamine is approximately 8.47E-11 cm3/(molecule * s). At 500,000 OH radicals / cm3 (approximate 24-hour mean in central), this corresponds to a half-life of 4.5 hours. The hydrolysis of isophorone diamine as a function of pH was studied according to OECD TG 111. At pH 4,7 and 9, less than 10% of the test substance were observed to hydrolyse at 50 °C within a period of 5 days, demonstrating hydrolytically stability in the environment. Isophorone diamine was found to be not readily biodegradable (EU method C.4 A "DOC Die-Away Test) and the calculated BCF value shows a low potential for bioaccumulation.