Registration Dossier
Registration Dossier
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EC number: 416-140-4 | CAS number: 145650-60-8
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study obtained through inquiry process; SNIF file obtained from ECHA.
Data source
Reference
- Reference Type:
- other: SNIF
- Title:
- Unnamed
- Year:
- 1 994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Body responsible for the test
- IUPAC Name:
- Body responsible for the test
- Test material form:
- not specified
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- Identity and concentration of auxiliary solvent for dispersal: 96.0 mg 1-Methyl-2-pyrrolidon und 4.0 mg Polyoxy-ethylen-sorbitan-monooleat (TWEEN 80)/L
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 240 mg CaCO3/L
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 8.7 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 8.7 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 8.7 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Details on results:
- %Concentration loss over test: 82 ... 93
No effects noted at and above the level of water solubility.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The acute toxicity of the test substance to aquatic invertebrates has been determined in a test with Daphnia Magna according to OECD Guideline 202. The EC50 (48h) and the EC100 (48h) were > 8.7 mg/L, the NOEC = 8.7 mg/L (48h). Hence, it can be stated that there is no toxicity in the range of the water solubility (insoluble) of the test substance. Therefore, the test substance is considered not to be harmful to aquatic invertebrates.
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