Registration Dossier
Registration Dossier
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EC number: 416-140-4 | CAS number: 145650-60-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study obtained through inquiry process; SNIF file obtained from ECHA.
Data source
Reference
- Reference Type:
- other: SNIF
- Title:
- Unnamed
- Year:
- 1 994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Body responsible for the test
- IUPAC Name:
- Body responsible for the test
- Test material form:
- not specified
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- Identity and concentration of auxiliary solvent for dispersal: 96.0 mg 1-Methyl-2-pyrrolidon und 4.0 mg TWEEN 80/L
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
Test conditions
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 46.9 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 46.9 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- growth rate
- Details on results:
- %Concentration loss over test: 20 ... 80
No effects noted at and above the level of water solubility.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The acute toxicity of the test substance to aquatic algae has been determined in a test with Scenedesmus subspicatus (new name: Desmodesmus subspicatus) according to OECD Guideline 201. The EC50 (72h) was > 46.9 mg/L and the NOEC (72h) = 46.9 mg/L (based on growth rate). Hence, it can be stated that there is no toxicity in the range of the water solubility (insoluble) of the test substance. Therefore, the test substance is considered not to be harmful to aquatic algae.
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