Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Boiling point

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The predicted boiling point of quinine is in the range from 422 - 495°C.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
456 °C

Additional information

The predicted boiling point of 450.64°C is based on the adapted Stein and Brown method, by Epi Suite v4.11. The estimation by calculation of the boiling point given by the ChemSpider database is 495°C. And the calculation of the Marrero and Gani model, using ChemProp, resulted in a boiling point of 422.99°C. The predicted boiling point of quinine is in the range from 422 - 495°C. For the boiling point a mean value (456°C) is assumed. Since the boiling point has not been measured, it is not possible to evaluate the estimation by calculation. Furthermore, in the study published by Dobbie, 1879 quinine was heated in a capillary tube in a paraffin bath and decomposed at 256 -257 °C. Thus, it is possible that quinine decomposed before reaching the boiling point. This is an indication, that there are no experimental studies on the boiling point available.