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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Handbook with reliable values.Reliability score 2 on the basis of the weight of evidence found during review of public documents.
Qualifier:
no guideline followed
Principles of method if other than guideline:
not applicable: handbook data
GLP compliance:
not specified
Type of method:
other: handbook data
Specific details on test material used for the study:
- Name of test material: Talc (Mg3H2(SiO3)4)
- Substance type: inorganic
- Physical state: solid
Water solubility:
< 0.1 mg/L
Temp.:
25 °C
Remarks on result:
other: Insoluble in water
Details on results:
Insoluble in water
Conclusions:
Interpretation of results: insoluble (< 0.1 mg/L)
Insoluble in water.Talc is practically insoluble in water
Executive summary:

Insoluble in water.Talc is practically insoluble in water

Endpoint:
water solubility
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Study period:
not applicable
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
QSAR prediction: US EPA accepted QSAR method for organic chemicals properties assessment.
Qualifier:
no guideline required
Principles of method if other than guideline:
QSAR method (WSKOW v1.42)
GLP compliance:
no
Remarks:
QSAR method
Type of method:
other: QSAR
Water solubility:
0.421 mg/L
Temp.:
25 °C
pH:
7
Remarks on result:
other: WSKOW v1.42

Overview of QSARs estimations onWater Solubility of Talc (Mg3H2(SiO3)4)

 

 

 

 

 

Method

 

Results

Remarks

Reference

QSAR estimate

                Water Sol: 0.421 mg/L

 

SMILES : O=[Si](O)O[Mg]O[Si](=O)O[Mg]O[Si](=O)O[Mg]O[Si](=O)O

CHEM : Benzenesulfonic acid, dodecyl-, calcium salt

MOL FOR: H2 O12 Si4 Mg3

MOL WT : 379.27

WSKOW v1.42 Results

Log Kow (estimated) : -9.40

Log Kow (experimental): not available from database

Water Solubility at 25 deg C (mg/L): 0.421

 

 

Valid with restrictions (2);

QSAR method;

Estimated values

 

 

Conclusions:
Interpretation of results : slightly soluble (0.1-100 mg/L)
Substance is predicted by QSAR method (EPI Suite v 4.1/WSKOW v1.42 ) to be slightly soluble ( 0.421 mg/l) in water.
Executive summary:

Substance is predicted by QSAR method (EPI Suite v 4.1/WSKOW v1.42 ) to be slightly soluble ( 0.421 mg/l) in water.

Description of key information

Insoluble in water.Talc is practically insoluble in water.

Substance is predicted by QSAR method (EPI Suite v 4.1/WSKOW v1.42 ) to be slightly soluble ( 0.421 mg/l) in water.

Key value for chemical safety assessment

Water solubility:
0.1 mg/L
at the temperature of:
25 °C

Additional information

Insoluble in water.Talc is practically insoluble in water.

Substance is predicted by QSAR method (EPI Suite v 4.1/WSKOW v1.42 ) to be slightly soluble ( 0.421 mg/l) in water.