Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 31 Jan - 01 Apr 2022
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- Water Solubility. January 24, 2014
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- Water Solubility. July 27, 1995
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Version / remarks:
- Water Solubility: Column Elution Method; Shake Flask Method. March 1998
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- < 2 µg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 10 µg/L
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- 7.4
- Key result
- Water solubility:
- < 2 µg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 20 µg/L
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- 7.4
- Conclusions:
- The water solubility of the test substance is estimated to be < 2.0 µg/L at 20 °C and pH 7.4.
Reference
Preliminary Test
The content of test material dissolved in the water sample was < 2.0 µg/L.
Main Study
No test material was detected in the samples taken at 24, 48 and 72 hours. The analyzed concentrations are therefore reported to be below the lowest calibration standard. The pH of the aqueous samples was 7.4.
No test material was detected in the pre-treated sample from the blank water mixture which corresponds with a water solubility of < 2.0 µg/L.
Conclusion
The slow-stirring flask method was applied for the determination of the water solubility.
The water solubility of the test materialat 20°C was < 2.0 µg/L.
The pH of the aqueous samples was 7.4.
Description of key information
The water solubility of the test material at 20°C was < 2.0 µg/L (OECD Guideline 105, slow stirring flask method).
The limit of quantification (LOQ) was assessed at 10 µg/L in water.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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