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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1979
Report date:
1979

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Method: BASF-Test; The test was performed according to Smith et al. (1944). J. Ind. Hyg. Tox. 26: 269
GLP compliance:
no
Test type:
other: inhalation hazard test
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-methyl-6-(4-methylcyclohex-3-en-1-ylidene)hept-2-ene
EC Number:
207-805-8
EC Name:
2-methyl-6-(4-methylcyclohex-3-en-1-ylidene)hept-2-ene
Cas Number:
495-62-5
Molecular formula:
C15H24
IUPAC Name:
4-(1,5-dimethylhex-4-en-1-ylidene)-1-methylcyclohexene
Constituent 2
Chemical structure
Reference substance name:
(4S)-1-methyl-4-(6-methylhepta-1,5-dien-2-yl)cyclohexene
EC Number:
610-461-5
Cas Number:
495-61-4
Molecular formula:
C15H24
IUPAC Name:
(4S)-1-methyl-4-(6-methylhepta-1,5-dien-2-yl)cyclohexene
Constituent 3
Chemical structure
Reference substance name:
6-methyl-2-(4-methylcyclohex-3-enyl)hept-2,5-diene
EC Number:
241-610-9
EC Name:
6-methyl-2-(4-methylcyclohex-3-enyl)hept-2,5-diene
Cas Number:
17627-44-0
Molecular formula:
C15H24
IUPAC Name:
4-(1,5-dimethylhexa-1,4-dien-1-yl)-1-methylcyclohexene

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
whole body
Vehicle:
air
Details on inhalation exposure:
GENERATION OF TEST ATMOSPHERE / CHAMBER DESCRIPTION
- A saturated atmosphere was generated by bubbling 200 l/h air at 20 ° C through a substance column of about 5 cm above a fritted glass disc in a glass cylinder for 7 hours.

TEST ATMOSPHERE
- No analytical determination of the atmosphere concentration was performed. The nominal concentration was calculated as the quotient of the amount of test substance weight loss during the exposure and the amount of air used during the exposure.
Analytical verification of test atmosphere concentrations:
no
Remarks:
concentration was estimated based on the test substance weight loss
Duration of exposure:
7 h
Concentrations:
13.74 mg/l
No. of animals per sex per dose:
6
Control animals:
other: not applicable
Details on study design:
- Necropsy of survivors performed: yes
- Other examinations performed: clinical signs and body weight
- Duration of observation period following administration: 14 days

Results and discussion

Mortality:
No mortality within 7h of exposure
Clinical signs:
other: no effects observed
Body weight:
normal bw development
Gross pathology:
No test substance related effects observed

Applicant's summary and conclusion