Registration Dossier
Registration Dossier
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EC number: 423-300-7 | CAS number: 128554-52-9
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The substances biodegradation has been assessed based on read-across results from two comparable substances. Based on the results it is considered that the substance is not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The results from two comparable substances have been read-across to assess the substances potential for biodegradation.
Study Conducted on Read-across substance EC No. 434 -430 -9 (EA-3098)
Determination of 'ready' biodegradability: carbon dioxide (CO2) evolution test (modified Sturm test) with EA-3098.
The study procedure was based on EEC directive 92/69, C.4-C, December 1992, OECD guideline No. 301 B July 17, 1992 and ISO Standard 9439 (1999).
The Theoretical CO2production (ThCO2) of EA-3098 was calculated to be 2.71 mg CO2/mg.
EA-3098 was a white powder and was treated as 100% pure. EA-3098 was tested in duplicate at 32 mg per 2 Litres, corresponding to 12 mg TOC/L. The organic carbon content was based on the molecular formula.
Since EA-3098 was poorly soluble in water, weighed amounts of EA-3098 were added to the test bottles containing medium with microbial organisms and mineral components. To this end, 10 mL of Milli-RO water was added to each weighing bottle containing the test substance. After vigorous mixing (vortex) the resulting suspension was added quantitatively to the test medium. The test solutions were continuously stirred during the test.
Furthermore, the test medium was daily swirled around to ensure optimal contact between the test substance and the test organisms, since the test substance tended to float on the water surface.
The relative degradation values calculated from the measurements performed during the test period revealed no significant degradation of EA-3098 (7% after 29 days).
In the toxicity control, EA-3098 was found not to inhibit microbial activity.
In conclusion, EA-3098 was not readily biodegradable under the conditions of the modified Sturm test performed.
Study Conducted on Read-across substance EC No. 423 -300 -7 (Amide#71)
The test substance attained 5% degradation after 29 days and cannot be considered to be readily biodegradable.
Based on the results it is considered that the substance is not readily biodegradable.
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